American Research Journal of Biosciences

Cell signaling pathways are important for cellular communications and control different cellular processes of growth, differentiation, and apoptosis. There are many ameliorations or magnifications of these pathways in cancer. Hepatocellular carcinoma (HCC) is one of the cancer diseases in which many signals are stimulated or inhibited. Moreover, the rate of the signaling pathway is linked to the production of the reactive oxygen species (ROS) and the antioxidant mechanism. Ras/Raf/MEK is one of the important pathways that was intensively studied in HCC and affected by ROS.