Duygu Bilgin Mehmet CelikMumtaz Takir
In about two-thirds of patients with primary hyperparathyroidism, Tc-99m sestamibi scintigraphy
allows the determination of parathyroid adenoma and the surgeon to plan appropriate surgery. In our study,
in the patients with the diagnosis of primary hyperparathyroidism; we aimed to investigate the relationship
between serum calcium (Ca), phosphorus (P) and parathyroid hormone (PTH) levels and Tc-99m sestamibi
parathyroid scintigraphy.
Material and Methods: The study was conducted between January 2015 and January 2018 in the Department
of Endocrinology and Metabolism Diseases of Göztepe Training and Research Hospital, Istanbul Medeniyet
University. A retrospective analysis of the files of the patients diagnosed as primary hyperparathyroidism
with clinical, biochemical and ultrasonographic findings was performed. A total of 79 patients (68 females, 11
males) who underwent parathyroid scintigraphy were included in the study. Age distribution of the patients
was similar in both gender (women 22-83, men 19-79 years). Scintigraphic evaluation was indicated as positive
or negative. Serum Ca, P and PTH levels were compared to scintigraphy results.
Results: In 38 patients (female: 32, male: 6), parathyroid scintigraphy was reported as suspicious for adenoma.
Adenoma was not detected in 33 patients (female: 29, male: 4). In 8 patients (female: 7, male: 1), differentiation
between parathyroid adenoma and thyroid nodule could not be made. Mann Whitney Test was used to
determine the relationship between the presence of adenoma and independent variables. According to this
test, the presence of adenoma was significantly associated with PTH and Ca levels, while it w
